?How does dysregulation of the mTOR Signaling Pathway contribute to disease

Dysregulation of the mTOR Signaling Pathway has been implicated in various diseases, including cancer, metabolic disorders, neurodegenerative diseases, and autoimmune disorders. For example, hyperactivation of mTOR signaling is often observed in cancer cells, promoting uncontrolled cell growth and proliferation. Conversely, insufficient mTOR activity can lead to metabolic disorders such as insulin resistance. Understanding these dysregulated states can provide insights into targeted therapeutic interventions.

?What are some therapeutic strategies targeting the mTOR Signaling Pathway

Several therapeutic strategies target the mTOR Signaling Pathway to modulate its activity for therapeutic benefit. These include mTOR inhibitors such as rapamycin and its analogs, which are used in cancer treatment to inhibit aberrant cell growth. Additionally, lifestyle interventions such as dietary restrictions and exercise can indirectly regulate mTOR activity. Furthermore, ongoing research is exploring combination therapies and novel drug targets within the mTOR pathway to address various diseases effectively.

mTOR Signaling Pathway effects Tutorial

What will you learn in this course?

Understand the molecular mechanisms of the mTOR signaling pathway and its role in cellular growth and metabolism.
Identify how mTOR regulates protein synthesis, cell proliferation, and nutrient sensing in different biological contexts.

Analyze the impact of mTOR signaling on immune response, neuronal function, and cellular adaptation to environmental changes.
Evaluate the implications of mTOR pathway dysregulation in diseases such as cancer, metabolic disorders, and neurodegeneration.

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Lessons | 3

00:12:50

mTOR Signaling Pathway Regulation by the Lysosome

00:18:38

mTOR Signaling Pathway mTOR Complexes Regulation and Downstream effects

00:08:50

AKT Signaling Pathway Regulation and Downstream Effects

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Nora_taallah

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2025-07-14

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19 Lessons

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mTOR Signaling Pathway course, in this course we will learn about the mTOR Signaling Pathway, a vital biological pathway regulating cellular growth, metabolism, and proliferation. Understanding mTOR's role is crucial as it impacts various cellular functions, including growth, metabolism, protein balance, neuronal cell regulation, and immune response. Through this course, you'll gain insights into how mTOR influences these processes and its significance in cellular adaptation under diverse physiological and environmental conditions.

mTOR Signaling Pathway effects

Medical

How to Get The Certificate

mTOR Signaling Pathway Regulation by the Lysosome

mTOR Signaling Pathway mTOR Complexes Regulation and Downstream effects

AKT Signaling Pathway Regulation and Downstream Effects

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