Question 1

?What role do genetic mutations play in causing thalassemia, and how are these mutations inherited

Accepted Answer

Thalassemia is primarily caused by mutations in the genes responsible for hemoglobin production. These mutations result in reduced or abnormal hemoglobin levels, leading to the characteristic symptoms of thalassemia. The condition is typically inherited in an autosomal recessive pattern, meaning that individuals must inherit two copies of the mutated gene (one from each parent) to develop thalassemia.

Question 2

?Are there any environmental factors that can influence the development of thalassemia, and if so, how do they interact with genetic predispositions

Accepted Answer

While thalassemia is primarily a genetic disorder, certain environmental factors such as exposure to radiation, toxins, or infections during pregnancy may exacerbate or modify the severity of the condition. Additionally, factors such as ethnicity and family history can influence the risk of inheriting thalassemia. Understanding the interplay between genetic predispositions and environmental influences is essential for accurate diagnosis and management of thalassemia.

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